Japanese Knotweed Supreme - 120 Capsules | Supreme Nutrition Products

Japanese Knotweed (Fallopia japonica, or You Ji Hu Zhang in Chinese) is native to eastern Asia. It is most famously known for containing high amounts of resveratrol. Unlike foods like grapes or drinking wine, Japanese Knotweed contains mostly trans-resveratrol, which is the form best absorbed and used in ones body. Resveratrol is a type of phenolic compound called stilbenes and acts as an antioxidant. Japanese Knotweed also contains other beneficial components such as emodin, flavonoids (including rutin and quercetin), oleanolic acid, etc.

Supreme Nutrition Products believe that whole plants (not an extract) often work better than extracts that alter the normal ratios found in nature. Resveratrol is the main and best known component of Japanese Knotweed, but as shown in studies below, there is great synergy between the components of Japanese Knotweed, which have benefits that either isolate does not possess on its own.

One of the most studied benefits of resveratrol are its benefits with reducing cardiovascular disease. It has been shown to decrease low-density lipoprotein–cholesterol oxidation and platelet aggregation as well as having anti-atherosclerotic and vasorelaxation action. New studies have also shown how it can induce autophagy and regenerate myocardial ischemic tissue treated with stem cells. In a study on rats, resveratrol decreased inflammatory cell infiltration, decreased and cardiac fibrosis.

With resveratrol being a known anti-inflammatory, it has been looked at to help with arthritis. A recent study showed resveratrol suppresses apoptosis and inflammatory signalling through its actions on the NF-κB pathway in human chondrocytes. Also it has been shown that resveratrol is an effective inhibitor of chondrocyte apoptosis in vitro by Inhibiting IL-1β–Induced stimulation of caspase-3. Similar to taking a non-steroidal anti-inflammatory drugs, it inhibits COX-2–derived prostaglandin E2 synthesis. Injection of resveratrol into the knees of those suffering from osteoarthritis showed that it might protect cartilage against the development of experimentally induced inflammatory arthritis.

For more information and supporting research please visit the complete product page and write-up at: Japanese Knotweed Supreme